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-: Past Lab Members :-
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Dr. Puthalakath V Hamsa
Puthalakath Laboratory Principal Research Fellow Department of Biochemistry La Trobe University
Victoria 3086 Phone: +61 3 9479 5226 Fax: +613 9479 2467
Email: h.puthalakath@latrobe.edu.au
http://www.latrobe.edu.au/biochemistry/lab/puthalakath/index.htm
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Ph.D in 1995 |
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Dr. Hamsa's Present work : |
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Dr. Pradeep Kachroo
Kachroo Laboratory Associate Professor Department of Plant Pathology
201F Plant Science Building
Email : pk62@uky.edu. |
Ph.D in 1995 |
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Dr. Kachroo's Present work : Plants are challenged by a diverse range of microbial pathogens and insect pests and have evolved countermeasures to resist most potential invaders. The outcome of the interaction of plants with a given pathogen is governed by several factors, including the genotype, the physiological state of the plant, environmental signals and, any specific interactions that might occur between the activated signaling pathways. Plants resist pathogen infection by inducing a defense response that is targeted specifically to combat invasion by the pathogen. In many cases, the induction of these responses is accompanied by localized cell death at the site of pathogen entry, which often is able to restrict the spread of pathogen to cell within and immediately surrounding the lesions. This phenomenon, known as the hypersensitive response, is one of the earliest visible manifestation of induced defense response and resembles programmed cell death in animals. Concurrent with hypersensitive response development, defense reactions are triggered locally and in parts distant from the site of primary infection. This phenomenon, known as systemic acquired resistance, is one of the most studied induced defense responses and is accompanied by a local and systemic increase in endogenous salicylic acid (SA) and a concomitant upregulation of a large set of defense genes. Among various signaling molecules proposed to modulate defense responses, SA and jasmonic acid (JA) are widely believed to be the global regulators of plant defense signaling. These phytohormones elicit distinct responses and undergo extensive cross talk, which is likely to influence the amplitude and magnitude of various signals leading to a resistance response. JA and Methyl JA, collectively termed jasmonates, are potent biological regulators in plants that are formed in a multi step process initiated by oxygenation of the fatty acid (FA)-linolenic acid. Upon pathogen attack, FAs are liberated from their esterified forms and converted into oxylipins, a group of oxygenated FA derivatives. The enzymatic and non-enzymatic oxygenation of FAs results in the generation of a wide variety of compounds, many of which are found in plants and animals. In addition to their role as precursors of oxylipins, free FAs can also act as signaling messengers, regulate membrane fluidity and serve as an energy reserve. The overall goal of our research is to help understand how specific signaling pathways are induced during host-pathogen interaction, how these pathways communicate with each other and the molecular mechanisms underlying such regulations. We are using Arabidopsis (www.arabidosis.org) as a model plant system and are studying its interaction with a viral pathogen turnip crinkle virus (TCV) and an oomycete pathogen Peronospora parasitica. With regards to signaling mechanisms our main interest is to decipher the role of fatty acid signaling pathways in plant defense.
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Dr. Naweed I Naqvi
Senior Principal Investigator Temasek Life Science Laboratory 1 Research Link, National University of Singapore Singapore 117604
Phone : (65)-68727493 (O); (65)-67730683(R) Mob : (65)-98297657
Email : naweed@tll.org.sg
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Ph.D in 1995 |
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Dr. Naqvi's Present work : My research group explores the basic molecular-genetic mechanisms underlying fungal pathogenesis. The long-term goal being the elucidation of specific developmental and physiological programs evolved by fungal pathogens to infect and colonize host plants. Presently, we utilize the blast fungus Magnaporthe grisea, and its host Rice, as a model pathosystem for understanding fungal virulence and host specificity. We rely on molecular genetics, cell biology, biochemistry and functional genomics as tools to understand the molecular and regulatory basis of the infection-related development in fungal pathogens and to elucidate the underlying basis of the fungus-host interactions. We initially established and utilized a novel forward-genetics approach to identify mutant derivatives of the blast fungus. We focus on the functional characterization of non-pathogenic mutants identified in the primary screening process. We are particularly interested in mutants that represent non-allelic lesions in pathways controlling host surface sensing, metabolism, signal transduction, osmoregulation, organellar and membrane biogenesis, ion homeostasis, targeted secretion etc. We also study the secondary metabolism associated with fungal virulence, and the host-specific regulation of these metabolic events during plant disease.
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| Dr. Mihali Raval - Pandya |
Ph.D in 1996 |
| Dr. Mandar N Dave |
Ph.D in 1998 |
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Dr. Aardra Potnis - Kachroo Assistant Professor,
Department of Plant Pathology Phone : 859-257-7445 x 81292 (office)
http://www.ca.uky.edu/agcollege/plantpathology/people/index.html |
Ph.D in 2000 |
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Dr. Aardra Kachroo's Present work : PLANT MICROBE INTERACTION The current research in my lab is focused on deciphering defense-signaling pathways in Arabidopsis and soybean plants using mutant analysis and virus-induced gene silencing to examine gene functions. We are interested in dissecting resistance signaling to viral, bacterial and fungal pathogens, and are particularly interested in examining the interconnection between normal metabolic pathways and host defense. Our previous work has implicated fatty acid and glycerol metabolism in the Arabidopsis resistance response. Current research is focused on deciphering the various regulatory roles of fatty acids and glycerol in plants, and will potentially identify downstream defense-related protein/gene targets, that also participate in the plant’s metabolic pathways.
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| Dr. Gopal Iyer |
Ph.D in 2003 |
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Dr. Malali Gowda
Director, The Genomics Facility Centre for Cellular and Molecular Platforms The National Centre for Biological Sciences Bangalore 580 065, India.
Mob : 09620836478
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Ph.D in 2004 |
| Dr. Sanjay Bhave |
Ph.D in 2004 |
| Dr. Sachin Tendulkar |
Ph.D in 2004 |
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Dr. R.C. Venu
Postdoctoral Associate University of Arkansas USDA - ARS Dale Bumpers National Rice Research Centre 2890 HWY 130 East, Stuttgart, AR 72160
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Ph.D in 2006 |
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Dr. Subhankar Roy-Barman
Assistant Professor Dept. of Biotechnology National Institute of Technology, Durgapur Mahatma Gandhi Avenue Durgapur - 713 209 West Bengal, India
Phone : +91 343 22755209; Fax : +91 343 2547375 Mob : +91 9433269277
Email : sroybarman@gmail.com
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Ph.D in 2006 |
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Dr. Roy-Barman's present work : Molecular Plant Microbe interaction Molecular plant pathology with special interest in understanding of molecular plant-microbe interaction, using rice-blast fungus model patho-system and functional genomics approaches. Specifically the goals include understanding mechanisms defense response in the monocot host and uncovering the mechanisms of fungal pathogenesis.
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| Dr. Vaishali J Patel |
Ph.D in 2007 |
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Dr. Rajesh N Patkar
Post Doc Fellow Temasek Life Sciences Lab 1 Research Link, Temasek Life Sciences Lab, Singapore 117604
Phone : +65 68727491; Mob : +65 92260733
Email : rajanna.7@gmail.com, rajesh@tll.org.sg
http://www.tll.org.sg |
Ph.D in 2007 |
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Dr. Patkar's Present work : Fungal Patho-Biology We are exploring the basic molecular-genetic mechanisms underlying fungal pathogenesis. The long-term goal is to elucidate specific developmental and physiological programs evolved by fungal pathogens to infect and colonize host tissues. Presently, we are working on the blast fungus Magnaporthe grisea, and its host Rice, as a model pathosystem for understanding fungal virulence and host specificity. We rely on molecular genetics, cell biology, biochemistry and functional genomics as tools to understand the molecular and regulatory basis of the infection-related development in fungal pathogens and to elucidate the underlying basis of the fungus-host interactions. The research is currently focused on functional characterization of some of the interesting knock out strains.
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Dr. Tulika Munshi
Postdoctoral Fellow Phone: 0044 (0)20 7079 0799 (lab) |
Ph.D in 2007 |
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Dr. Munshi's Present work : Currently working on structural and functional characterisation of some Mycobacterial enzymes which are potential targets for drug development.
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Dr. Sanjay Jha
Assistant Professor Navsari Agricultural University Navsari |
Ph.D in 2008 |
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Dr. Devesh Suthar
Lecturer Dept of Biochemistry M.S. University of Baroda Baroda - 390 002 India
Mobile: +91-98245
83574
Email :
dev_su@yahoo.com |
Ph.D in 2008 |
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Dr. Suthar's present work : Bioprospecting of microbial endophytes: This work involves isolation and characterization of endophytes from selected medicinal plants. Currently, we are screening the endophyte isolates for their antimicrobial and antioxidant activities. The long term aim of this work is to explore and evaluate the potential of bioactive compounds produced by these endophytes for use in medical, agricultural, and industrial arenas. Metabolic engineering to improve productivity in industrial microorganisms: Here we make use of an metabolic engineering approach that is based on the observation that the heterologous expression of Vitreoscilla hemoglobin (VHb) enhances growth and productivity in various prokaryotic and eukaryotic hosts under oxygen-limiting conditions.
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Dr.. Archana Patkar (Gupta)
Research Associate Tel: +65 6316 2927 Email: archna.16g@gmail.com |
Ph.D in 2008 |
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Dr. Patkar's Present work : Epigenetics in Malarial parasite Plasmodium Falciparum. The aim of the project is to characterize global effects of antimalarial drugs on P. falciparum using ChIP on Chip technology. |
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Dr. Bishun Deo Prasad
Post
Doc Fellow Phone: 519-661-2111 Ext- 80262 Email: dev.bishnu@gmail.com, bprasad2@uwo.ca |
Ph.D in 2008 |
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Dr. Prasad's Present work : Exploring the basic molecular mechanism by which brassinosteroids (BRs), a group of naturally occurring plant steroidal compounds, confer tolerance in plants to a range of environmental stresses.
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Copyright © 2003
Bioinformatics Centre , Dept. of Microbiology and Biotechnology Centre
M.S.University of Baroda,Baroda, India 390002
Phone:91-0265-2794396 , Fax: 91-265-2792508
Last updated: Thursday, 28 October, 2010 01:12 PM